AYONNE
Skin Analyzer
Skin Analyzer
March 2025 Update
In March 2025, Hims & Hers discontinued Apostrophe and canceled all subscriptions. If you're looking for personalized skincare without a prescription, Ayonne's AI-powered skin analysis and vegan OTC products are built for exactly that.
Apostrophe was a popular teledermatology platform that offered custom prescription skincare formulas — primarily tretinoin, niacinamide, azelaic acid, and clindamycin compounds — paired with online provider consultations. In 2022, Hims & Hers Health, Inc. acquired the company for approximately $190 million.
On March 7, 2025, Hims & Hers shut down the Apostrophe service entirely to refocus resources on its weight-loss drug business. All customer subscriptions were canceled, accounts were closed, and the apostrophe.com domain now redirects to forhers.com — which does not offer the same personalized dermatology service.
Thousands of users who relied on Apostrophe for their skincare routines were left without a provider. If you're one of them, you have options — and for most skincare concerns, you may not need a prescription at all.
What Apostrophe Gave You
What Ayonne Gives You
Most of what Apostrophe prescribed has effective OTC counterparts. Here's what to look for instead.
| Apostrophe Rx | OTC Alternative | Why It Works |
|---|---|---|
| Tretinoin (Rx) | Retinol | OTC form of vitamin A. Gentler on skin, effective without a prescription. Results take longer but come with fewer side effects. |
| Prescription Niacinamide 4% | Niacinamide | Available OTC at effective concentrations (2-5%). Reduces pores, calms inflammation, and strengthens skin barrier. |
| Azelaic Acid (Rx) | Vitamin C + Glycolic Acid | Brightening and exfoliation without a prescription. Vitamin C targets dark spots while glycolic acid promotes cell turnover. |
| Clindamycin (Rx antibiotic) | Salicylic Acid | A BHA that penetrates pores to fight acne from within. No antibiotic resistance risk, available over the counter. |
Apostrophe Rx
Tretinoin (Rx)
OTC Alternative
OTC form of vitamin A. Gentler on skin, effective without a prescription. Results take longer but come with fewer side effects.
Apostrophe Rx
Prescription Niacinamide 4%
OTC Alternative
Available OTC at effective concentrations (2-5%). Reduces pores, calms inflammation, and strengthens skin barrier.
Apostrophe Rx
Azelaic Acid (Rx)
OTC Alternative
Brightening and exfoliation without a prescription. Vitamin C targets dark spots while glycolic acid promotes cell turnover.
Apostrophe Rx
Clindamycin (Rx antibiotic)
OTC Alternative
A BHA that penetrates pores to fight acne from within. No antibiotic resistance risk, available over the counter.
Apostrophe's “personalization” was a questionnaire — you described your skin in words, a provider reviewed your answers, and they prescribed a formula. It worked, but it relied on self-reporting. Most people struggle to accurately describe their own skin conditions.
Ayonne takes a fundamentally different approach. Our AI uses computer vision (MediaPipe face mesh + Claude AI analysis) to actually look at your skin from photos. It detects conditions like acne, fine lines, dark spots, dehydration, enlarged pores, and uneven texture — then generates a skin health score and personalized product recommendations.
The result: personalization based on what your skin actually looks like, not what you think it looks like. And it's free, instant, and available any time — no appointment, no waiting room, no $60 monthly fee.
Whatever you were treating with Apostrophe, we have a guide for the best OTC alternatives.
Free AI skin analysis. No prescription. No subscription. Just results.
Start Your Free Skin Analysis